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Complete information for yap1 gene (protein coding), yes1 associated transcriptional regulator, including Aberrant expression of this gene in adult tissues is associated with tumorigenesis. Function, proteins, disorders, pathways, orthologs, and expression.

This gene encodes a protein belonging to the raf family of serine/threonine protein kinases This gene encodes a transcription factor containing a pou homeodomain that plays a key role in embryonic development and stem cell pluripotency This protein plays a role in regulating the map kinase/erk signaling pathway, which affects cell division, differentiation, and secretion.

Complete information for ciita gene (protein coding), class ii major histocompatibility complex transactivator, including

This gene encodes pyruvate carboxylase, which requires biotin and atp to catalyse the carboxylation of pyruvate to oxaloacetate The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. The protein encoded by this gene represents the alpha subunit of cbf and is thought to be involved in the development of normal hematopoiesis